1.) Why is the same gene annotated several times for a single variation?
Genes have numerous alternative transcripts which are often differentially affected by genetic variations. Therefore SG-ADVISER takes into account each individual transcript. This leads to more confusing, but more accurate interpretation of genetic variation.
2.) What does "*" mean in the "ConservedXXXway" results?
PhyloP values are given for base-specific variations (snps/deletions) but cannot be produced for insertions, therefore, a '*' is assigned.
3.) How many Wellderly individuals are included in the allele frequency calculation?
As of now 387 individuals with more on the way.
4.) What about non-human organisms?
Development of SG-ADVISER for non-human organisms is underway.
Please post your questions in the forum!